Εργαστήριο Παθολογικής Ανατομικής και Κυτταρολογίας

Ανάπτυξη και συντήρηση λειτουργίας εργαστηρίου υψηλών προδιαγραφών και υψηλού κόστους (βλέπε στοιχεία Επιτροπής Ερευνών).

Πιστοποίηση από UK NEQAS σε εργαστηριακές εξετάσεις KRAS, BRAF, EGFR,c-ΚΙΤ, HER2.

Εργαστήριο αναφοράς για μοριακές εξετάσεις EGFR, ALK - Σύμβαση παροχής υπηρεσιών με Εταιρεία Ογκολόγων Παθολόγων Ελλάδος (Ε.Ο.Π.Ε.) (1 από τα 4 στην Ελλάδα).

Ερευνητικές δημοσιεύσεις (ενδεικτικά αναφέρονται): a) Clinical significance of the fluctuation of primary biliary cirrhosis-related autoantibodies during the course of the disease. Gatselis NK, Zachou K, Norman GL, Gabeta S, Papamichalis P, Koukoulis GK, Dalekos GN. Autoimmunity. 2013 Jun 19. [Epub ahead of print], b) Evaluation of current prognostic and predictive markers in breast cancer: a validation study of tissue microarrays. Batistatou A, Televantou D, Bobos M, Eleftheraki AG, Kouvaras E, Chrisafi S, Koukoulis GK, Malamou-Mitsi V, Fountzilas G. Anticancer Res. 2013 May;33(5):2139-45, c) IgA antibodies against deamidated gliadin peptides in patients with chronic liver diseases. Gatselis NK, Zachou K, Norman GL, Tzellas G, Speletas M, Gabeta S, Germenis A, Koukoulis GK, Dalekos GN.Clin Chim Acta. 2012 Oct 9;413(19-20):1683-8, d) Comparative study of spatial localization of HER-2 and CEP17 signals and of HER-2/CEP17 ratios, in "thin" and "thick" tissue sections. Kouvaras E, Papandreou CN, Daliani DD, Athanasiadis A, Koukoulis GK. Breast. 2012 Feb;21(1):34-9, e) High serum levels of HIF-1α in psoriatic patients correlate with an over-expression of IL-6. Vasilopoulos Y, Sourli F, Zafiriou E, Klimi E, Ioannou M, Mamuris Z, Simos G, Koukoulis G, Roussaki-Schulze A. Cytokine. 2013 Apr;62(1):38-9, f) Ancient schwannoma involving the median nerve: a case report and review of the literature. Malizos K, Ioannou M, Kontogeorgakos V. Strategies Trauma Limb Reconstr. 2013, g) Hidradenocarcinoma of the temporal area successfully treated with concomitant electrochemotherapy and radiotherapy. Kyrgias G, Kostopoulou E, Zafiriou E, Zygogianni A, Skarlatos J, Roussaki-Schulze A, Theodorou K. Head Neck Oncol. 2013 Feb 6;5(2):14, h) Different patterns of p16 immunoreactivity in cervical biopsies: correlation to lesion grade and HPV detection, with a review of the literature. Kostopoulou E, Samara M, Kollia P, Zacharouli K, Mademtzis I, Daponte A, Messinis IE, Koukoulis G. Eur J Gynaecol Oncol. 2011;32(1):54-61. Review, i) An unusual case of Primary Effusion Lymphoma with aberrant T-cell phenotype in a HIV-negative, HBV-positive, cirrhotic patient, and review of the literature. Nepka C, Kanakis D, Samara M, Kapsoritakis A, Potamianos S, Karantana M, Koukoulis G. Cytojournal. 2012;9:16, j) Sequence variations in the FII, FV, F13A1, FGB and PAI-1 genes are associated with differences in myocardial perfusion. Satra M, Samara M, Wozniak G, Tzavara C, Kontos A, Valotassiou V, Vamvakopoulos NK, Tsougos I, Aleporou-Marinou V, Patrinos GP, Kollia P, Georgoulias P. Pharmacogenomics. 2011 Feb;12(2):195-203, k) Mismatch DNA Repair mRNA Expression Profiles in Oral Melanin Pigmentation Lesion and Hamartomatous Polyp of a Child With Peutz-Jeghers Syndrome. Vageli DP, Doukas SG, Markou A. Pediatr Blood Cancer. 2013 May 15, l) Mismatch repair hMSH2, hMLH1, hMSH6 and hPMS2 mRNA expression profiles in precancerous and cancerous urothelium. Vageli DP, Giannopoulos S, Doukas SG, Kalaitzis C, Giannakopoulos S, Giatromanolaki A, Koukoulis GK, Touloupidis S. Oncol Lett. 2013 Jan;5(1):283-294. Epub 2012 Oct 19.