The project ClEver BALLOON aims at the development of a new medical device for the treatment of arterial disease, an endovascular drug coated balloon catheter (DCB). The product is expected to achieve effective local administration of everolimus, a known but innovative for this specific application drug, with the use of an innovative “ClEver” drug release system that has been patented by the project partners with two international patents. The project includes development of prototypes, in vivo, in vitro and in silico studies.