The Structural and Functional Biochemistry Laboratory serves the educational and research needs in the disciplines of biochemistry (intermediate metabolism, synthesis and nucleic acid metabolism, synthesis, structure and function of proteins), structural biochemistry, proteomics, structural genomics, regulation and Metabolic Control of Enzymes and the implementation of all the above in Analytical Biochemistry, Enzymology Clinical Biochemistry, Food biochemistry, Chemical Biology, structure-driven drug design and Biophysics as applied to Biochemical Sciences.
Control of Glycogen Metabolism.
Elucidation of the control, diversity and biological functions of deadenylases.
Structure-based design of enzyme inhibitors.
Structural basis of carbohydrate recognition by lectins.
Characterization and function of the mitochondrial steroid hormone receptors. Mechanisms of intracellular trafficking.
Molecular Modeling.
University of Thessaly Research Committee. "Proteomic analysis of the entomopathogeny of Pseudomonas entomophila". Grant No. 4098. PI: Μ.Κοntou.
University of Thessaly Research Committee. "Studies on function and structure of poly(A) specific ribonuclease, PARN". Grant No. 3743. PI: Nikolaos Balatsos.
Ministry of National Education and Religion Affairs Project Eraklitos IΙ: «Τranscriptomic and proteomic analysis of the most important parasite of the olive, the insect Bactrocera oleae, with emphasis on systems gender segregation and resistance to insecticides». M.Κοntou, collaborator.
University of Thessaly Research Committee. "Structure and function studies of the poly(A) specific ribonuclease PARN". Grant No.3743. PI: Nikolaos Balatsos.
University of Thessaly Research Committee. "Role of steroid hormone receptors in mitochondria functions" Grant No. 4088.14.01. PI: Α.–Μ. Psarra.
General Secretariat for Research and Technology, Joint Research Projects Greece – France (2010–2012): Human angiogenin as a molecular target for the development of new anticancer agents. PI: D.D. Leonidas.
ARISTEIA, Structure–assisted Design, Synthesis, and Evaluation of Bioactive compounds for type 2 Diabetes mellitus, PI: D.D. Leonidas.
Two Fast Protein Liquid Chromatography Systems (FPLC).
Nano-robot for protein crystallization.
Two-dimensional Electophoresis System.
ELISA plate reader.
Speed-vac.
γ-Counter.
Micro-equipment (electrophoresis, centrifuges etc).
Structure based design and biochemical evaluation of new hypoglycaemic agents.
Structure based design and assessment of new anti-inflammatory, and anti-cancer agents.
| Surname | Name | Profession-Position | Phone Number | |
|---|---|---|---|---|
|
Demetres
|
Leonidas
|
Director
|
ddleonidas@bio.uth.gr
|
+30 2410 565278
|
|
Kontou
|
Maria
|
Assistant Professor
|
mkontou@bio.uth.gr
|
+30 2410 565281
|
|
Balatsos
|
Nikos
|
Assistant Professor
|
balatsos@bio.uth.gr
|
+30 2410 565261
|
|
Papadopoulos
|
George
|
Assistant Professor
|
geopap@bio.uth.gr
|
+30 2410 565249
|
|
Psarra
|
Anna–Maria
|
Assistant Professor
|
ampsarra@bio.uth.gr
|
+30 2410 565221
|
|
Skamnaki
|
Vasiliki
|
Senior Researcher
|
vskamnaki@bio.uth.gr
|
+30 2410 565281
|
|
Katsandi
|
Anastassia
|
Researcher
|
+30 2410 565297
|
|
|
Hatzileontiadou
|
Demetra
|
Researcher
|
+30 2410 565297
|
|
|
Kiritsis
|
Athanasios
|
Researcher
|
+30 2410 565297
|
|
|
Gorgogietas
|
Byron
|
Researcher
|
+30 2410 565297
|